My name is Helen and the reason I put this website together, with the support of others, is to raise awareness around the world about Hormone (Endocrine) and Allergy/Atopy problems.  The information provided on this website is for men, women, and children.  Awareness about possible Hormone Allergy is growing as more people report it.

This website is also to provide information and to spread research on a range of hormone and atopic conditions, and possible associated conditions.

Click the cover to buy the book

To read the full story of what happened to my Mother and her family as mentioned on this website download my book – A Clock with Bells and Butterflies, Helen Jane Marsh, Amazon Kindle Store, 2017.  If you have a problem accessing it via Amazon search, try Google search.

*Please see the Hormone Changes Section on this site for a self or family pattern checklist*

The hormone system and the immune system is considered to be closely linked and work together for homeostasis, otherwise known as internal balance.

Examples collected so far

I am interested in the effects on the body and brain due to chemical imbalances such as that relating to hormones, neurotransmitters, and enzymes.  As well as amines of the brain including histamine involved in allergy and atopy.

I myself have a family history of hormone and atopy problems, including pernicious anaemia, thyroid diseases and thyroid nodules, severe PMS, hay fever, asthma, food allergies/food sensitivities, and skin sensitivities.  This goes hand in hand with gluten protein intolerance and class 2 latex protein allergy including latex fruit/food syndrome (see Anaphylaxis Campaign UK and Allergy UK).  Collectively the conditions are part of the Autoimmune Group *

The Thyroid gland is considered to be a Butterfly shaped gland at the base of the neck and has an important role to play in the functions of the body.

I finally obtained my Mother’s  extensive health notes following the Freedom of Information Act 2000 and due to poor communication by healthcare staff who were involved with her in previous years I was at last able to see the full hormone and atopic picture in the records.  Along with this my Mother’s children, including me, were developing the same or similar conditions.  By chance after 2010 I was to have contact with others which helped to affirm that hormone and atopy may often co-exist within an individual or family.

The Autoimmune group appears wide presenting as different patterns or examples, and rarely does an individual or family seem identical.   Perhaps this is why so much more research is needed for these conditions which can be both overwhelming and all-consuming.

Both my parents suffered as a consequence of my Mother having hormone and atopic problems with poor diagnosis and treatment for many years.  My Father often struggled to work and care for his wife who was not always fully functioning, and also care for his children who had a Mother who was at times apathetic through no fault of her own.

This website is dedicated to my parents in memory of their unsettled lives spanning decades and the name ‘Aldris’ is a combination of their forenames.  This website is also for them for their endurance in the face of adversity and misfortune whereby my Mother had an impairment and my Father was her Caregiver.

Please see the Carer’s Trust Charity and Carers.org if you are in need of support – Carers and those they care for especially with stigmatised conditions.

My Mother had blood tests during pregnancies, which showed anaemia, however she was not given a full blood test for around thirty years whilst under the care of psychiatric services as well as other services and when she finally did her thyroid hormone levels were deranged which may explain why she was often tired and cold with achy legs for many years.

My Mother also had pre-eclampsia during pregnancies and scientific research suggests a possible link to the prediction of future thyroid diseases in women who had pre-eclampsia during pregnancy.  My mum also had baby blues during and after pregnancy, and premenstrual syndrome (PMS) as well as other endocrine disorders have been linked to it.

Hormone and protein disorders are interesting and the PMS2 gene provides instructions for making proteins (Genetics Home Reference).

I now know that underactive thyroid disease in particular may come with depression, psychosis, hallucinations, and early onset dementia (amnesia) if left undiagnosed and untreated over time.  It can also cause myxedema which my Mother developed over time – see the myxedema madness link below.

My Mother eventually did receive thyroxine which her body must have been craving –  over decades my Mother was instead given an array of mental health drugs and ECT treatment for depression and psychosis as well as being labelled with other disorders that are questionable. 

I believe that my Mother had a weakened state of mind due to lack of thyroxine.

In time I was to also learn that cardiovascular disease may also be involved with hormone (endocrine) disorders including thyroid disease – my Mother developed imbalanced cholesterol hormone levels, raised blood pressure, strokes, cardiac events, and renal failure.

*New Guidelines for diagnosis and treatment of thyroid disease during pregnancy and postpartum, 9/1/2017, You & Your Hormones website (Society for Endocrinology).*

*Experts met to address the need to improve hormone tests, Society for Endocrinoloy.

  • Neurodiversity Celebration.
  • PMS Sadness – see the Hormone Changes Section on this site.
  • The Butterfly Scheme – reaching out to people with memory loss.
  • Neurohormones, gynacological endocrinology, and general endocrinology.
  • Hormones divided into two major groups on the basis of structure – Derived from amino acids such as amines, peptides, and proteins.  Derived from Lipids such as steroids.
  • 2% of DNA contains the code to produce proteins, the remaining 98% was thought to be non-coding junk but increasing evidence suggests otherwise.
  • Omics Revolution and Exposome Research.
  • Hormone and Protein Related Cancers.
  • Carol Petersen at Women’s International Pharmacy.  Dr Katharina Dalton and Dr. Al Plechner – progesterone research and hyperestrogen state (cortisol activity and the effects on the immune system).  Histamine and Estrogen.
  • Latex Allergy and Latex Fruit/Food Syndrome – Anaphylaxis Campaign UK and Allergy UK.
  • Latex Allergy and Latex Food Syndrome with Cannabis/Marijuana plant intolerance – effects on the mind such as psychosis.
  • Schizophrenia:  The Latex Allergy Hypothesis, by Harold D Foster PhD, which refers to mental illness over various centuries including the 1800s (also see John Bostock and Allergy 1844).
  • Latex Allergy, Hevian, dental work and gutta -percha relationship.
  • Brain Allergies: How Sensitivities to Food and Other Substances Can Effect the Mind, by Patrick Holford (includes Cerebral Allergy).
  • How Gluten/Latex Protein Foods destroy other digestive enzymes/villi which help digest other proteins such as dairy proteins and egg proteins.
  • How do genes direct the production of proteins? Genetics at Home Reference, NIH.
  • Poultry fed on grains and egg production – food intolerance/allergy to grains, eggs, and poultry.
  • Animals fed on grasses/grains and dairy production – food intolerance/allergy to dairy produce.
  • Low Fodmap Diet.
  • Angiodema and Allergy.
  • Genetic basis of the latex-fruit syndrome:  Association with HLA class II alleles in a Spanish population, Carlos Blanco MD PhD and associates.     Spain and the Philippines – endocrine and allergy rates with migration to other countries (also incidence of nasopharyngeal sinus problems and cancer in the Asian population).
  • Alzheimer’s News – drug may halt early stages of memory loss as brain proteins cleared away.
  • TSH (thyroid) and histamine (allergy) – amines and the brain.
  • Maternal Hypothyroidism in pregnancy affects math score in offspring.
  • ADHD and hyperestrogen research.
  • Maternal Hypothyroidism/Hyperthyroidism and fetal brain development.
  • Insulin (diabetes) and histamine (allergy) – amines and the brain,
  • Hypothyroidism presenting as psychosis:  Myxedema madness by TW Heinrich, 2003.
  • Thyroid disease and Hallucinations.  Hypothyroidism and Hallucinations.
  • Thyroid dysfunction and mental disorders – Thyroid Foundation.
  • Thyromind website – psychiatric disorders or neurological/endocrine disorders?
  • The psychiatric disorders – which accompany hypo and hyper thyroid disease, losing touch with reality and becoming delirious or hallucinating.  Psychiatric disorders or neurological/endocrine disorders?
  • Thyroid diseases and the central nervous system.
  • Thyroid Dysfunction and Mental Disorders by Elnasser Elmaghraby. 15/3/16.
  • Hypothyroidism:  An Important Diagnostic Consideration for the Psychiatrist.
  • Violence, hormones, and mental health.
  • Gender Transition (female to male, or male to female) and a self or family history of hormone and atopy problems.

The Tardy Development of UK Neurology, by J Walton.

The Fantastical World of Hormones, by Professor John Wass.

5 different types of Diabetes (clusters 1-5), March 2018, Professor Leif Groop, Lund University, Sweden.  

The Hubble Test (Biobank UK) – ageing, frailty, and mobility.

The Ipswich Test for Diabetes.

Foodsmatter Website, 5 Lawn Road, London.

Collectively my Maternal family pattern or example includes:

  • Pernicious Anaemia (refer to connection of PA to thyroid disease and gluten protein disorder).
  • Hypoactive (underactive) and hyperactive (overactive) thyroid disease, which includes a non-typical type with symptoms of both hyper and hypo thyroidism.
  • Thyroid Nodules (refer to thyroid nodules and Premenstrual Syndrome).
  • Severe Premenstrual syndrome (also refer to associated conditions).
  • Baby Blues
  • Atopy of various kinds.
  • Cardiovascular disease.
  • Hyperhidrosis of the hands and feet (see nervous system and connection to thyroid disease).
  • Learning differences, including dyslexia and Asperger’s syndrome (Autism).

I also have a Paternal family history of Pes Cavus.

Please refer to the Immune System Section on this site regarding Latex Allergy and Latex Fruit/ Food Syndrome.

I could explain to you more about various hormone disorders, protein disorders, atopic disorders, and other disorders that exist but I feel that you may wish to undertake most of your own learning and research so have decided to add some links, references, and key words that I have discovered over time which may be useful.

Whether you are male or female you might want to see all the sections on this site as they may cross reference and may also give insight into various health problems which you are not aware of – during my lifetime I have come across many people with various health problems and have often held my breath for something better for them and for myself when research has not advanced…Please donate to a charity mentioned on this website.

  • Differing Definitions in other countries other than Britain:  There is some concern that the American Psychiatric (APA) criteria focuses predominately on psychiatric symptoms which are defined under the term PMDD, rather than PMS, and is within the Diagnostic and Statistical Manual of Mental Disorders (DSM-V).  The American Congress of Obstetricians and Gynecologists (ACOG) apparently focuses equally on psychiatric and physical symptoms in its definition of PMS.  The World Health Organization (WHO) apparently focuses predominantly on psychiatric symptoms defined under the term Premenstrual Tension Syndromes (PMTS) within the International Statistical Classification of Diseases and Related Health Problems (ICD-10)

In Britain it is considered that current PMS terminology should be maintained because the restrictive term of PMDD refers to only one type of severe form of PMS, and PMDD excludes some women with severe PMS due to the strict criteria (not all women with PMS suffer dysphoria and historical articles may refer more to euphoria/hysteria). 

This may not refer to you but I would like to suggest that you look at these links on the internet to help you understand possible relationships of hormone and allergy.  Both male and female offspring of women with hormone problems may have atopy:

  • Premenstrual Syndrome and Atopy by A Atton-chamla 1980 (reactive allergy): a double-blind clinical evaluation of treatment with a gamma-globulin/histamine complex.
  • Asthma and Atopy: endocrine or metabolic conditions? L Forbes 2005.
  • Diagnosis and management of premenstrual syndrome – metaphysics and premenstrual disorders. Dr Malcolm John Dixon, BMJ, 3/6/2011, refers to Pluto and the scepticism about illness that cannot be seen through diagnostic testing that has been developed so far.
  • Managing menstrual problems of girls with disabilities presents medical dilemma.  Professor Anne Garden, 23/4/2013.
  • Premenstrual Syndrome Genes 2007 and 2017.
  • Endogenous and Exogenous Sex Steroid Hormones in Asthma and Allergy in Females:  Protocol For a Systemic  Review, Bright Nwaru, Ulugbek Nurmatov & Aziz Sheikh, 2016.
  • The Pituitary – Trefoil Factor 3 gene protein and endometriosis, PMS, cancer, immunity, and food regulation.  Peritoneal cavity and endometriosis.
  • Hormone and Protein related cancers in males and females – see Zoladex LA in the Immune System section on this website.
  • Cancer, Thyroid diseases, and other endocrine disorders.
  • Cancer and Immunology.
  • Thyroid Cancer Types – Pipillary (BRAF gene and protein encoding, chromosome 7).
  • Autism and Genes:  What causes Autism? (chromosome 7 and 15).
  • The Autism and Allergy Overlap, The Autism File.

Please see symptoms of PMS in the Hormone Changes section on this website.

Courtesy of the National Endocrine and Metabolic Diseases Information Service:

  • Thyroid axis function during the menstrual cycle in women with premenstrual syndrome. gov.  Psychoneuroendocrinology, 1995. Girdler, Pedersen, Light.  Susan Girdler’s team were also involved in discovering the PMS gene in 2007 and I am not keen on the term PMDD as myself and other women did not have depression and rather euphoria/hysteria was experienced.
  • Thyroid function in women with premenstrual syndrome. gov. J Clin Endocrinol Metab. 1993.  Schmidt, Grover, Roy-Byrne, Rubinow.
  • Thyroid function and treatment in premenstrual syndrome, 1990. PubMed, Nicoli, Mulligan, Gribble, Harkins, Melar, Roberts.

Take part in Menopause Research – British Menopause Society and Menopause Science (USA).

Breakthrough research to help women affected by early menopause, March 2018.

The Truth about the Menopause, 26/11/18, Mariella Frostrup.

Animals in our world never fail to amaze me and I have seen how animals help humans in many ways.  From the pollination of plants humans eat to survive, to the comfort they give us without question, and the things that they sense we need when we cannot such as working dogs.

No animal in our universe should be mistreated, whether intentional or not.  Pets are often chosen by humans without choice and whilst the owner or owners are trying to figure them out, the pet is trying to figure them out and miss-communication can occur.  How can you blame a dog for using the kitchen as a toilet whilst you were out at work for too long or others in the house went to bed and did not let them out beforehand…whatever pet you have make sure you take the time to understand what it needs in your care and do not allow it to be mentally or physically abused, misunderstood, needlessly blamed, lonely, excluded, bored, fearful, and make sure it has adequate exercise, food, water, medical attention, place to sleep, space to roam without being stuck in a cage or tank, and make sure the environment in which they are expected to live is not a stressful and hostile environment and allow them a quiet area to escape from noise if they need to.  If you remove a puppy or kitten from its litter and they no longer have their parent or sibling(s) you are replacing them so they will need you to interact with them in many ways such as through play.  A puppy may need adequate socialization in your home and community before the age of three months old and if that key time is missed your puppy may have problems…try asking your local veterinary staff for advice before getting a pet or ask them for advice if you have any problems understanding your pet.

Please see the following links on the internet:

  • Pet respect.
  • Captive Animals Protection Society.
  • Action against cruelty to animals.
  • Dogs Trust.
  • Four Paws UK.
  • Cat’s Protection.
  • Service dogs in the UK and Europe.
  • Guide dogs for the blind.
  • Medical detection and bio-detection dogs.
  • Diabetic and epilepsy dogs.
  • Seizure detecting cats.
  • Avalanche and snow dogs.
  • Born free foundation.
  • UK world animal protection (WSPA).
  • WWF
  • Blue cross.
  • Animal shelters in your area.
  • The donkey and mule sanctuary.
  • Brooke Action for working horses and donkeys.
  • Animal aid.
  • Compassion in world farming.
  • Rescue dog to super dog.
  • Humane Society International.
  • Other animal protection charities not mentioned on this website.

It is unfortunate that animals have to be experimented on in order to help humans combat diseases and think of the sacrifice that is made in order for this to happen.


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